Alistair M. Senior, PhD

Post-Doctoral Research Fellow

Evolutionary Ecology, Behaviour & Nutrition

My research is primarily in the fields of behavioural and evolutionary ecology, using computational and statistical techniques.

I mainly use agent-based models, sometimes called individual-based models in ecology, and meta-analysis / comparative-analysis, but also study wild populations and captive model organisms.

During my PhD I worked on the effects that environmental factors have on sex determination in fish. After completing my PhD I shifted focus, and now look at questions surrounding the interactions between ecology, life history and the evolution of nutritional strategies.

Given current obesity epidemics, this aspect of biological research is more relevant than ever before.

Please scroll down for publications list.



School of Life and Environmental Sciences

School of Mathematics and Statistics

Charles Perkins Centre

The University of Sydney

Current and Previous Collaborators / Co-Authors

Catherine E Grueber

David Raubenheimer

Eduardo SA Santos

Edward C. Holmes

Gabriel Machovsky-Capuska

Gerard Closs

Jemma Geoghegan

Jerome Buhl

Katie O’Dwyer

Malgorzata Lagisz

Mark Lokman

Martin Krkosek

Mathieu Lihoreau

Mike Charleston

Sheri L. Johnson

Shinichi Nakagawa

Stephen J Simpson

Tsukushi Kamiya

Volker Grimm


If you cannot access the articles below through the links provided on the DOIs, I am very happy to provide reprints - contact me on the email address above.

Journal of Gerontology: Biological Sciences (2019)

in press

Branched chain amino acids, cardiometabolic risk factors and outcomes in older men: the Concord Health and Aging in Men Project.

Le Couteur, D.G., Ribeiro, R.V., Senior, A.M., Hsu, B., Hirani, V., Blyth, F.M., Waite, L.M., Simpson, S.J., Naganathan, V., Cumming, R.G. & Handelsman, D.

Nutrients (2019)

in press

Of older mice and men: branched chain amino acids and body composition.

Ribeiro, R.V., Solon-Biet, S.M., Pulpitel, T., Senior, A.M., Cogger, V.C., Clark, X., O’Sullivan, J., Koay, Y.C., Hirani, V., Blyth, F.M., Beibel, M.J., Waite, L., Naganathan, V., Cumming R.G., Handelsman, D.J., Simpson, S.J. & Le Couteur, D.G.

Oikos (2019)

online early

Parasites and stable isotopes: a comparative analysis of isotopic discrimination in parasitic trophic interactions.

Thieltges, D., Goedknegt, A., O’Dwyer, K., Senior, A.M. & Kamiya, T.

Proceedings of the Royal Society B (2019)

286: 20190393

Dietary macronutrient content, age-specific mortality and lifespan.

Senior, A.M., Solon-Biet, S.M., Cogger, V.C., Le Couteur D.G., Nakagawa, S., Raubenheimer, D & Simpson, S.J.

Current Biology (2019)

29: 1677-1682

Giant pandas are macronutritional carnivores.

Nie, Y., Wei, F., Zhou, W, Hu, Y., Senior, A.M., Wu, Q., Yan, L. & Raubenheimer, D

Nature Metabolism (2019)

1: 532-545

Branched chain amino acids impact health and lifespan indirectly via diet balance and appetite control.

Solon-Biet, S.M., Cogger, V.C., Pulpitel, T., Wahl, D., Clark, X., Bagley, E., Gregoriou, G.C., Senior, A.M., Wang, Q.P., Brandon, A.E., Perks, R., O’Sullivan, J., Koay, Y.C., Bell-Anderson, K., Kebede, M., Yau, B., Atkinson, C., Svineng, G., Dodgson, T., Wali, J.A., Piper, M.D.W., Juricic, P., Partridge, L., Raubenheimer, D., Cooney, G.J., Le Couteur, D.G. & Simpson, S.J.

Journal of the Royal Society Interface (2019)

16: 20180733

Macronutrient intakes and the lifespan-fecundity trade-off: a geometric framework agent-based model.

Hosking C.J., Raubenheimer, D., Charleston, M.A., Simpson, S.J. & Senior, A.M.

PLOS ONE (2019)

14: e0212796

Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis.

Morimoto, J. / Senior, A.M., Ruiz, K., Wali, J., Pulpitel, T., Solon-Biet, S.M., Cogger, V.C, Raubenheimer, D., Le Couteur, D.G., Simpson, S.J & Eberhard, J.

Obesity Reviews (2019)

20: 921-933

High-fat diets reduce male reproductive success in animal models: a systematic review and meta-analysis.

Crean, A.J. & Senior, A.M.

BMJ Open (2019)

9: e025291

Effect of nutrition interventions on diet related and health outcomes of Aboriginal and Torres Strait Islander Australians: a systematic review.

Gwynn, J., Sim, K., Searle, T., Senior, A.M., Lee, A. & Brimblecombe, J.

Cell Reports (2018)

25: 2234-2243

Comparing the effects of low protein, high carbohydrate diets and caloric restriction on brain aging in mice.

Wahl, D., Solon-Biet, S.M., Wang, Q., Wali, J., Pulpital, T., Clark, X., Raubenheimer, D., Senior, A.M., Sinclair, D., Cooney, G., de Cabo R., Cogger, V., Simpson, S.J. & Le Couteur, D.G.l.

Journal of Fish Diseases (2018)

41: 1733-1744

Quantitative analysis of the dose of white spot syndrome virus in shrimp.

Thuy, T.T.N, Senior, A.M., Culina, A., Santos, E.S.A, Vlak, J.M. & Zwart, M.P.

Journal of Animal Ecology (2018)

87: 1286-1298

The nutritional nexus: linking niche, habitat variability and prey composition in a generalist marine predator.

Machovsky-Capuska, G., Miller, M., R. O. Silva, F., Amiot, C., Stockin, K., Senior, A.M., Schuckard, R., Melville, D., & Raubenheimer, D.

Nutrients (2018)

10: 6

Associations of diet and physical activity with risk for gestational diabetes mellitus: a systematic review and meta-analysis.

Mijatovic, J., Capling, L., Cheng, S., Louie, J., Cheung, W., Markovic, T., Ross, G., Stamatakis, E., Senior, A.M., Brand-Miller, J. & Flood, V.M.

Biological Reviews (2018)

93: 1108-1124

Intergenerational effects of nutrition on immunity: systematic review and meta-analyses.

Grueber, C.E., Gray, L.J., Morris, K.M., Simpson, S.J. & Senior, A.M.

British Journal of Nutrition (2017)

118: 130-143

Diet quality and its implications on the cardio-metabolic, physical and general health of older men: the Concord Health and Ageing in Men Project (CHAMP).

Ribeiro, R.V., Hirani, V., Senior, A.M., Gosby, A.K., Cumming, R.G., Blyth, F.M., Naganathan, V., Waite, L.M., Handelsman, D.J., Kendig, H., Seibel, M.J., Simpson, S.J., Stanaway, F., Allman-Farinelli, M. & Le Couteur, D.G.

Current Biology (2017)

27: 2397-2404

Gut microbiota modifies olfactory-guided microbial preferences and foraging decisions in Drosophila.

Wong, A.C., Wang, Q., Morimoto, J., Senior, A.M., Lihoreau, M., Neely, G.G., Simpson, S.J. & Ponton, F.

Behavioural Ecology (2017)

28: 1021-1029

Macronutrient selection of free-ranging urban Australian white ibis (Threskiornis moluccus)

Coogan, S., Machovsky-Capuska, G., Senior, A.M., Martin, J., Major, R & Raubenheimer, D.

Philosophical Transactions of the Royal Society B (2017)

372: 20160238

Collective foraging in spatially complex nutritional environments.

Lihoreau, M., Charleston, M., Senior, A.M., Clissold, F., Raubenheimer, D., Simpson, S.J., & Buhl, J.

Nutrients (2017)

9: 646

Metabolic effects of high glycemic index diets: a systematic review and meta-analysis of feeding studies in mice and rats.

Campbell, G.J., Senior, A.M. & Bell-Anderson, K.S.

Biology Letters (2017)

13: 20170057

Dietary restriction increases variability in longevity.

Senior, A.M., Nakagawa, S., Raubenheimer, D., Simpson, S.J. & Noble, D.W.A.

BMC Biology (2017)

15: 18

Meta-evaluation of meta-analysis: 10 appraisal questions for biologists.

Nakagawa, S. / Noble, D.W.A. / Senior, A.M. / Lagisz, L.

Ecology (2016)

97: 3293-3299

Heterogeneity in ecological and evolutionary meta-analyses: its magnitude and implication.

Senior, A.M., Grueber, C.E. Kamiya, T., Lagisz, M., O Dwyer, K., Santos, E.S.A. & Nakagawa, S.

Biological Reviews (2016)

91: 1065-1080

Effect of maternal diet on offspring coping styles in rodents: a systematic review and meta-analysis.

Besson, A., Lagisz, M., Senior, A.M., Hector, K. & Nakagawa, S.

Biological Journal of the Linnean Society (2016)

119: 430-435

Condition and reproductive investment in the western mosquitofish Gambusia affinis: little evidence for condition-dependent sex biased investment.

Senior, A.M. / Lim, J.N., Adolfsson, S., Lamatsch, D.K. & Nakagawa, S.

Proceedings of the Royal Society B: Biological Sciences (2016)

283: 20160727

Pathogen population bottlenecks and adaptive landscapes: overcoming the barriers to disease emergence.

Geoghegan, J.L. / Senior, A.M. & Holmes, E.C.

American Journal of Physiology - Heart and Circulatory Physiology (2016)

310: H1064-H1070

Dietary macronutrients and the aging liver sinusoidal endothelial cell.

Cogger, V, Mashani, M., Solon-Biet, S., Senior, A.M., Warren, A., O Reilly, J., Tung, B.T., Svistounov, D., McMahon, A., Fraser, R., Raubenheimer, R., Holmes, A., Simpson, S.J. & Le Couter, D.

Evolution, Medicine and Public Health (2016)

2016: 244-255

Meta-analysis of variance: an illustration comparing the effects of two dietary interventions on variability in weight.

Senior, A.M., Gosby, A., Lu, J., Simpson, S.J. & Raubenheimer, D.

Mammalian Biology (2016)

81: 523-526

Macronutritional consequences of food generalism in an invasive mammal, the wild boar.

Senior, A.M. / Grueber, C, Machovsky-Capuska, G.E., Simpson, S.J. & Raubenheimer, D.

Trends in Ecology and Evolution (2016)

31: 355-365

The multi-dimensional nutritional niche.

Machovsky-Capuska, G.E. / Senior, A.M., Simpson, S.J. & Raubenheimer, D.

Royal Society Open Science (2016)

3: 150638

Adaptive collective foraging in groups with conflicting nutritional needs.

Senior, A.M., Lihoreau, M., Charleston, M., Buhl, J., Raubenheimer, D. & Simpson, S.J.

Proceedings of the National Academy of Sciences of the USA (2016)

113: 4170-4175

Virological factors that increase the transmissibility of emerging human viruses.

Geoghegan, J.L. / Senior, A.M. / Di Giallonardo, F. & Holmes, E.C.

Journal of Fish Biology (2016)

88: 1631-1641

Habitat-related specialisation of lateral-line system morphology in a habitat-generalist and a habitat-specialist.

Vanderpham, J.P., Nakagawa, S., Senior, A.M. & Closs, G.P.

Marine Biology (2016)

163: 1-14

Sex-specific macronutrient foraging strategies in a monomorphic marine predator: the Australasian gannet.

Machovsky-Capuska, G.E., Senior, A.M., Benn, E., Tait, A., Schuckard, R., Stockin, K., Cook, W., Ogle, M., Barna, K., Melville, D., Wright, B., Purvin, C. & Raubenheimer, D.

Cellular and Molecular Life Sciences (2016)

73: 1237-1252

The impact of low-protein high-carbohydrate diets on aging and lifespan.

Le Couter, D.G., Solon-Biet, S., Cogger, V.C., Mitchell, S.J., Senior, A.M., de Cabo, R., Raubenheimer, D., & Simpson, S.J.

Frontiers in Psychology (2016)

7: 18

Social network analysis and nutritional behavior: an integrated modeling approach.

Senior, A.M. / Lihoreau, M., Buhl, J., Raubenheimer, D. & Simpson, S.J.

Behavioural Ecology (2016)

27: 219-227

Dietary protein selection in a free-ranging urban population of common myna birds.

Machovsky-Capuska, G.E., Senior, A.M., Zantis, S.P., Barna, K., Cowieson, A.J., Pandya, S., Pavard, C., Shiels, M. & Raubenheimer, D.

Fish and Fisheries (2016)

17: 143-164

Sperm traits of masculinised fish relative to wild-type males: a systematic review and meta-analyses.

Senior, A.M., Johnson, S.L. & Nakagawa, S.

Ecology of Freshwater Fish (2016)

25: 174-189

Life history variation in a species-complex of non-migratory galaxiids.

Jones, P., Senior, A.M., Allibone, R.M. & Closs, G.P.

The American Naturalist (2015)

186: 649-659

An overlooked consequence of dietary mixing: a varied diet reduces inter-individual variance in fitness.

Senior, A.M., Nakagawa, S., Lihoreau, M., Simpson, S.J. & Raubenheimer, D.

PLOS Computational Biology (2015)

11: e1004111

Evolving nutritional strategies in the presence of competition: a geometric agent-based model.

Senior, A.M., Charleston, M., Lihoreau, M., Buhl, J., Raubenheimer, D. & Simpson, S.J.

Journal of Zoology (2015)

297: 184-193

Captive rearing affects growth but not survival in translocated juvenile tuatara.

Jarvie, S., Senior, A.M., Recio, M.R. Adolf, S., Seddon, & Cree, A.

PLOS ONE (2015)

10: e0118214

Sex specific marker development from transcriptome in the invasive mosquitofish Gambusia affinis.

Lamatsch, D.K., Adolfsson, S., Christiansen, G., Senior, A.M., Pichler, M., Ozaki, Y., Smeds, L., Schartl, M. & Nakagawa, S.

The Quarterly Review of Biology (2015)

90: 23-44

Ecological and evolutionary applications for environmental sex reversal of fish.

Senior, A.M., Lokman, P.M., Closs, G.P. & Nakagawa, S.

Conservation Genetics (2015)

3: 595-611

Toll-like receptor diversity in 10 threatened bird species: relationship with microsatellite heterozygosity.

Grueber, C.E., Knafler, G.J., King, T.M., Senior, A.M., Grosser, S., Robertson, B., Brekke, P., Harris, C.L.W.

Methods in Ecology and Evolution (2015)

6: 143-152

Meta-analysis of variance: ecological and evolutionary applications and beyond.

Nakagawa, S., Poulin, R., Mengersen, K., Reinhold, K., Engqvist, L., Lagisz, M. & Senior, A.M.

Molecular Ecology (2014)

23: 5151-5163

A quantitative review of MHC-based mating preference: the role of diversity and dissimilarity.

Kamiya, T., O’Dwyer, K., Westerdhal, H., Senior, A.M. & Nakagawa, S.

Evolution (2014)

68: 2306-2318

Heterogeneity in individual quality and reproductive trade-offs within species.

Lim, J.N. / Senior, A.M. & Nakagawa, S.

PLOS ONE (2014)

9: e103100

The evolutionary consequences of disrupted male mating signals: an agent-based modelling exploration of endocrine disrupting chemicals in the guppy.

Senior, A.M., Nakagawa, S. & Grimm, V.

New Zealand Journal of Ecology (2014)

38: 315-321

Effect on South Island Robins (Petroica australis) of pest control using aerially applied 1080 poison.

Schadewinkel, R.B., Senior, A.M., Wilson, D.J. & Jamieson, I.G.

Biological Invasions (2013)

15: 1765-1782

The practicality of Trojan sex chromosomes as a biological control: an agent based model of two highly invasive Gambusia species.

Senior, A.M., Krkosek., M. & Nakagawa, S.

Fish and Fisheries (2013)

14: 60-76

A comparative analysis of chemically induced sex reversal in teleosts: challenging conventional suppositions.

Senior, A.M. & Nakagawa, S.

Biological Reviews (2012)

87: 900-911

The fitness consequences of environmental sex reversal in fish: a quantitative review.

Senior, A.M., Lim, J.N. & Nakagawa, S.